Chiari I: Outcome

A points-based algorithm for prognosticating clinical outcome of Chiari malformation Type I with syringomyelia: results from a predictive model analysis of 82 surgically managed adult patients
J Neurosurg Spine. 2017 Nov 10:1-10. 

  • A team of specialist from the Sri Sathya Sai Institute of Higher Medical Sciences in Bangalore and the Christian Medical College, Vellore, India published a study in 82 adult patients with Chiari I malformation and syringomyelia. They evaluated factors that might predict outcome following surgery and found that patients with gait imbalance and motor deficits did not respond to surgery as well as those without these findings. They also found that patients with more pronounced Chiari I malformations were more likely to respond favorably to surgery.

Long term outcome of surgical treatment of Chiari Malformation without syringomyelia.
Giammattei L, Messerer M, Daniel RT, Aghakhani N, Parker F.
J Neurosurg Sci. 2017 Jul 4.

The Chiari Symptom Profile: development and validation of a Chiari-/syringomyelia-specific questionnaire.
Mueller DM, Oro' JJ.
J Neurosci Nurs. 2013 Aug;45(4):205-10.

Long-term results after posterior fossa decompression in syringomyelia with adult Chiari Type I malformation.
Alfieri A, Pinna G.
J Neurosurg Spine. 2012 Nov;17(5):381-7.

Long-term outcome of surgical management of adult Chiari I malformation.
El-Ghandour NM.
Neurosurg Rev. 2012 Oct;35(4):537-46; discussion 546-7.


Hayhurst C, Richards O, Zaki H, Findlay G, Pigott TJ.
Hindbrain decompression for Chiari - syringomyelia complex: an outcome analysis comparing surgical techniques.
Br J Neurosurg. 2008 Feb;22(1):86-91.

Zhang ZQ, Chen YQ, Chen YA, Wu X, Wang YB, Li XG.
Chiari I malformation associated with syringomyelia: a retrospective study of 316 surgically treated patients.
Spinal Cord. 2007 Nov 20; [Epub ahead of print]

Ono A, Suetsuna F, Ueyama K, Yokoyama T, Aburakawa S, Numasawa T, Wada K, Toh S.
Surgical outcomes in adult patients with syringomyelia associated with Chiari malformation type I: the relationship between scoliosis and neurological findings.
J Neurosurg Spine. 2007 Mar;6(3):216-21

McGirt MJ, Nimjee SM, Fuchs HE, George TM.
Relationship of cine phase-contrast magnetic resonance imaging with outcome after decompression for Chiari I malformations.
Neurosurgery. 2006 Jul;59(1):140-6; discussion 140-6.

Mueller D, Oro' JJ.
Prospective analysis of self-perceived quality of life before and after posterior fossa decompression in 112 patients with Chiari malformation with or without syringomyelia. 
Neurosurgical Focus 2005 Feb 15;18(2):ECP2. 
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