Chiari I: General

An Unusual Presentation of Chiari I Malformation.
Scheidler CS, Golomb MR.
J Child Neurol. 2012 Oct 3.

Familial Chiari malformation: case series.
Schanker BD, Walcott BP, Nahed BV, Kahle KT, Li YM, Coumans JV.
Neurosurg Focus. 2011 Sep;31(3):E1. doi: 10.3171/2011.6.FOCUS11104.

Craniocervical junction fusions in patients with hindbrain herniation and syringohydromyelia.
Fenoy AJ, Menezes AH, Fenoy KA. 

J Neurosurg 2008; Spine 9(1): 1-9

Milhorat TH, Bolognese PA, Nishikawa M, McDonnell NB, Francomano CA.
Syndrome of occipitoatlantoaxial hypermobility, cranial settling, and chiari malformation type I in patients with hereditary disorders of connective tissue.
J Neurosurg Spine. 2007 Dec;7(6):601-9.

Monzillo P, Nemoto P, Costa A, Rocha A.
Paroxysmal hemicrania-tic and Chiari I malformation: an unusual association.
Cephalalgia. 2007 Dec;27(12):1408-12. Epub 2007 Oct 18.

  • First reported case of Chiari malformation causing paroxysmal hemicrania and trigeminal neuralgia.

Hofkes SK, Iskandar BJ, Turski PA, Gentry LR, McCue JB, Haughton VM.
Differentiation between symptomatic Chiari I malformation and asymptomatic tonsilar ectopia by using cerebrospinal fluid flow imaging: initial estimate of imaging accuracy.
Radiology. 2007 Nov;245(2):532-40. Epub 2007 Sep 21.

Weisfeld-Adams JD, Carter MR, Likeman MJ, Rankin J.
Three sisters with Chiari I malformation with and without associated syringomyelia.
Pediatr Neurosurg. 2007;43(6):533-8.

  • First reported case of “three siblings in one family with confirmed CMI with or without syrinx.” A fourth daughter is unaffected.

Ono A, Suetsuna F, Ueyama K, Yokoyama T, Aburakawa S, Takeuchi K, Numasawa T, Wada K, Toh S.
Cervical spinal motion before and after surgery in patients with Chiari malformation type I associated with syringomyelia.
J Neurosurg Spine. 2007 Nov;7(5):473-7.

  • The effect of cranio-cervical decompression for CM-I on cervical spine motion has not been previously studied. The authors measured the amount of flexion and extension in 30 patients before and after surgery and found no detrimental effect on spine motion.

Felício AC, Godeiro-Junior Cde O, Borges V, Silva SM, Ferraz HB.
Hemifacial spasm in a patient with neurofibromatosis and Arnold-Chiari malformation: a unique case association.
Arq Neuropsiquiatr. 2007 Sep;65(3B):855-7.

Koç K, Anik Y, Anik I, Cabuk B, Ceylan S.
Chiari 1 Malformation with Syringomyelia: Correlation of Phase-Contrast Cine MR Imaging and Outcome.
Turk Neurosurg. 2007;17(3):183-92.

  • Cine MRI follow-up in 18 cases of CM-I and syringomyelia. Heterogenous spinal fluid flow seen pre-operatively improved or corrected to sinusoidal pattern following surgery.

Kamel MH, Mansour N, Kelleher MO, Aquilina K, Young S.
Association of intracranial hypertension without ventriculomegaly and Chiari malformation: a dangerous combination.
Br J Neurosurg. 2007 Aug 13;:1-3 [Epub ahead of print]

  • An unusual case of a person with a Chiari I malformation and raised intracranial pressure due to carcinomatous meningitis.

Sun X, Qiu Y, Zhu Z, Zhu F, Wang B, Yu Y, Qian B.
Variations of the position of the cerebellar tonsil in idiopathic scoliotic adolescents with a cobb angle >40 degrees: a magnetic resonance imaging study.
Spine. 2007 Jul 1;32(15):1680-6.

Boyles AL, Enterline DS, Hammock PH, Siegel DG, Slifer SH, Mehltretter L, Gilbert JR, Hu-Lince D, Stephan D, Batzdorf U, Benzel E, Ellenbogen R, Green BA, Kula R, Menezes A, Mueller D, Oro' JJ, Iskandar BJ, George TM, Milhorat TH, Speer MC.
Phenotypic definition of Chiari type I malformation coupled with high-density SNP genome screen shows significant evidence for linkage to regions on chromosomes 9 and 15.
Am J Med Genet A. 2006 Dec 15;140(24):2776-85. 

Osuagwu FC, Lazareff JA, Rahman S, Bash S.
Chiari I anatomy after ventriculoperitoneal shunting: posterior fossa volumetric evaluation with MRI.
Childs Nerv Syst. 2006 Nov;22(11):1451-6. Epub 2006 May 30. 

Banik R, Lin D, Miller NR.
Prevalence of Chiari I malformation and cerebellar ectopia in patients with pseudotumor cerebri.
J Neurol Sci. 2006 Aug 15;247(1):71-5. Epub 2006 May 6. 

Robenek M, Kloska SP, Husstedt IW.
Evidence of familial syringomyelia in discordant association with Chiari type I malformation.
Eur J Neurol. 2006 Jul;13(7):783-5. 

Szewka AJ, Walsh LE, Boaz JC, Carvalho KS, Golomb MR.
Chiari in the family: inheritance of the Chiari I malformation.
Pediatr Neurol. 2006 Jun;34(6):481-5. 

Buoni S, Zannolli R, di Bartolo RM, Donati PA, Mussa F, Giordano F, Genitori L.
Surgery removes EEG abnormalities in patients with Chiari type I malformation and poor CSF flow.
Clin Neurophysiol. 2006 May;117(5):959-63. Epub 2006 Mar 20. 

Murano T, Rella J.
Incidental finding of Chiari I malformation with progression of symptoms after head trauma: case report.
J Emerg Med. 2006 Apr;30(3):295-8. 

Makela JP.
Arnold-Chiari malformation type I in military conscripts: symptoms and effects on service fitness.
Mil Med. 2006 Feb;171(2):174-6. 

Sekula RF Jr, Jannetta PJ, Casey KF, Marchan EM, Sekula LK, McCrady CS.
Dimensions of the posterior fossa in patients symptomatic for Chiari I malformation but without cerebellar tonsillar descent.
Cerebrospinal Fluid Res. 2005 Dec 18;2:11. PMID: 16359556 [PubMed]

Iskandar BJ, Haughton V.
Age-related variations in peak cerebrospinal fluid velocities in the foramen magnum.
J Neurosurg. 2005 Dec;103(6 Suppl):508-11. 

Bauer AM, Mueller DM, Oro JJ.
Arachnoid cyst resulting in tonsillar herniation and syringomyelia in a patient with achondroplasia. Case report.
Neurosurg Focus. 2005 Nov 15;19(5):E14. Review. 

Prilipko O, Dehdashti AR, Zaim S, Seeck M.

Orthostatic intolerance and syncope associated with Chiari type I malformation.

J Neurol Neurosurg Psychiatry. 2005 Jul;76(7):1034-6. 

Mueller DM, Oro' J.
Chiari I malformation with or without syringomyelia and pregnancy: case studies and review of the literature.
Am J Perinatol. 2005 Feb;22(2):67-70. Review. 

Tubbs RS, Iskandar BJ, Bartolucci AA, Oakes WJ.
A critical analysis of the Chiari 1.5 malformation.
J Neurosurg. 2004 Nov;101(2 Suppl):179-83. 

Mueller DM, Oro' JJ.
Prospective analysis of presenting symptoms among 265 patients with radiographic evidence of Chiari malformation type I with or without syringomyelia.
J Am Acad Nurse Pract. 2004 Mar;16(3):134-8. 

Bejjani GK.
Association of the Adult Chiari Malformation and Idiopathic Intracranial Hypertension: more than a coincidence.
Med Hypotheses. 2003 Jun;60(6):859-63.

Aguiar PH, Tella OI Jr, Pereira CU, Godinho F, Simm R.
Chiari type I presenting as left glossopharyngeal neuralgia with cardiac syncope.
Neurosurg Rev. 2002 Mar;25(1-2):99-102. Review. 

Sinclair N, Assaad N, Johnston I.
Pseudotumour cerebri occurring in association with the Chiari malformation.
J Clin Neurosci. 2002 Jan;9(1):99-101. 

Mueller D.
Brainstem conundrum: the Chiari I malformation.
J Am Acad Nurse Pract. 2001 Apr;13(4):154-9. 

Kanpolat Y, Unlu A, Savas A, Tan F.
Chiari Type I malformation presenting as glossopharyngeal neuralgia: case report.
Neurosurgery. 2001 Jan;48(1):226-8. 

Allsopp GM, Karkanevatos A, Bickerton RC.
Abductor vocal fold palsy as a manifestation of type one Arnold Chiari malformation.
J Laryngol Otol. 2000 Mar;114(3):221-3. 

Ellenbogen RG, Armonda RA, Shaw DW, et al. 

Toward a rational treatment of Chiari I malformation and syringomyelia. 
Neurosurg Focus 2000; 8(3): E6

Milhorat TH, Chou MW, Trinidad EM, Kula RW, Mandell M, Wolpert C, Speer MC.
Chiari I malformation redefined: clinical and radiographic findings for 364 symptomatic patients.
Neurosurgery. 1999 May;44(5):1005-17.

Samii C, Mobius E, Weber W, Heienbrok HW, Berlit P.
Pseudo Chiari type I malformation secondary to cerebrospinal fluid leakage.
J Neurol. 1999 Mar;246(3):162-4. 

Atkinson JL, Weinshenker BG, Miller GM, Piepgras DG, Mokri B.
Acquired Chiari I malformation secondary to spontaneous spinal cerebrospinal fluid leakage and chronic intracranial hypotension syndrome in seven cases.
J Neurosurg. 1998 Feb;88(2):237-42. 

Wolf DA, Veasey SP 3rd, Wilson SK, Adame J, Korndorffer WE.
Death following minor head trauma in two adult individuals with the Chiari I deformity.
J Forensic Sci. 1998 Nov;43(6):1241-3.

Callaway GH, O'Brien SJ, Tehrany AM.
Chiari I malformation and spinal cord injury: cause for concern in contact athletes?
Med Sci Sports Exerc. 1996 Oct;28(10):1218-20. Review.  

Kasner SE, Rosenfeld J, Farber RE.
Spontaneous intracranial hypotension: headache with a reversible Arnold-Chiari malformation.
Headache. 1995 Oct;35(9):557-9.

Dyste GN, Menezes AH, VanGilder JC, et al. 

Symptomatic Chiari malformations. An analysis of presentation, management, and long-term outcome.
J Neurosurg 1989; 71(2): 159-168

Aboulezz AO, Sartor K, Geyer CA, Gado MH.
Position of cerebellar tonsils in the normal population and in patients with Chiari malformation: a quantitative approach with MR imaging.
J Comput Assist Tomogr. 1985 Nov-Dec;9(6):1033-6.